Представление

ПРЕДСТАВЛЕНИЕ

Приглашенный рофессор Казанского Федерального Университета и ведущий ученый Open Lab 'Двигательная Нейрореабилитация'. Ведущий специалист в области управления движениями, травмы спинного мозга, нейрореабилитации, восстановительной неврологии, нейрофизиологии и электрофизиологии.

Имеет опыт работы в ведущих вузах и научных организациях: университет Копенгагена, Дания; университет Луизвилля, США; университет Калифорнии, Лос Анджелес, США. Научные стажировки в университете Копенгагена, Дания; Postdoctoral Research Fellow, университет Луизвилля, США, () и университет Калифорнии, Лос Анджелес, США ()

Достижения включают публикации в ведущих рецензируемых журналах: Nature Neuroscience, J. of Neuroscience, European J Neurosci Neuroscience, J. of Neurophysiology, и др., авторство в более 80 научных статей, докладов, обзоров, учебников и патентов.

Является приглашенным рецензентом научных журналов и симпозиумов: J. of Neurophysiology, American J. of Primatology, Frontiers in Neuroprosthetics, International Symposium on Bio - and Medical Informatics and Cybernetics. Член ассоциаций: International Brain Research Organization, National Spinal Cord Injury Association, Society for Neuroscience, International Functional Electrical Stimulation Society

ОБРАЗОВАНИЕ

Медицинское высшее (08/1992 – 06/1998), Военно-медицинская академия, Санкт-Петербург, Россия

Интернатура по Неврологии (06/1998 – 07/1999), Отделение неврологии,

Военно-медицинская академия, Санкт-Петербург, Россия

Аспиранутра (09/1999 – 06/2002), Институт физиологии им. Павлова, Санкт-Петербург, Россия. Диссертация кандидата наук на тему: “Механизмы активации центральных генераторов шагания (CPG) при помощи электрической стимуляцией спинного мозга”.

ОПЫТ РАБОТЫ

Университет Копенгагена, Дания, Научный сотрудник (07/1999 – 08/1999)

Невропатолог (09/1999 – 10/2000) Отделение нейрохирургии, 23-я городская больница, Санкт-Петербург, Россия

Невропатолог (10/2000 – 07/2002) Клинико-диагностический центр “ONIKA”, Пушкин, Россия

Postdoctoral Research Fellow, Университет Луизвилля, США (2002 – 2004)

Postdoctoral Research Fellow, Университет Калифорнии, Лос Анджелес, США ()

Научный сотрудник консорциума исследований 'CRPF' (2005 – 2007)

Исследователь университета Калифорнии, Лос Анджелес, США, (2008 – 2011)

ПУБЛИКАЦИИ

Статьи (за 5 лет):

1.  Gad P, Lavrov IA, Shah P, Zhong H, Roy RR, Edgerton VR, Gerasimenko Y. (2013) Neuromodulation of motor-evoked potentials during stepping in spinal rats. Journal of Neurophysiology 110(6):1311-22 DOI: 10.1152/jn.00169.2013. IF-3.313

2.  Gad P, Woodbridge J, Lavrov I, Zhong H, Roy RR, Sarrafzadeh M, Edgerton VR. (2012) Forelimb EMG-based trigger to control an electronic spinal bridge to enable hindlimb stepping after a complete spinal cord lesion in rats. Journal of Neuroengineering and Rehabilitation 9:38 DOI: 10.1186/-38 IF-2.71

3.  Shah PK, Gerasimenko Y, Shyu A, Lavrov I, Zhong H, Roy RR, Edgerton VR. (2012) Variability in step training enhances locomotor recovery after a spinal cord injury. European J Neurosci Neuroscience 36(1):2054-62 DOI: 10.1111/j..2012.08106.x IF-3.886

4.  Nandra M, Lavrov I, Edgerton VR, Tai YC. (2011) A parylene-based microelectrode array implant for spinal cord stimulation in rats. Proceedings of the IEEE Eng Med Biol Soc 2011:. DOI: 10.1109/MEMSYS.2011.5734598 IF-0.508

5.  Fong AJ, Roy RR, Ichiyama RM, Lavrov I, Courtine G, Gerasimenko Y, Tai YC, Burdick J, Edgerton VR. (2009) Recovery of control of posture and locomotion after a spinal cord injury: solutions staring us in the face. Progress in Brain Research 175:393-418

6.  Gerasimenko YP, Shah P, Tillakaratne NJ, Lavrov I, Zhong H, Roy RR, Edgerton RV. (2009). Mechanisms underlying the regulation of different modes of locomotor behavior in adult chronic spinal rats. Journal of Physiological Science (Japan: Springer Tokyo) 59:451-451

7.  Grégoire Courtine, van den Brand R, Musienko PE, Gerasimenko YP, Zhong H, Roy RR, Lavrov I, V. Reggie Edgerton, and M. Sofroniev. (2009) Transformation of nonfunctional spinal circuits into functional and adaptive states after complete loss of supraspinal input. Nature Neuroscience 12:

8.  Gerasimenko Y, Musienko P, Bogacheva I, Moshonkina T, Savochin A, Lavrov I, Roy R. R, Edgerton VR. (2009) Propriospinal By-Pass of the Serotonergic System That Can Facilitate Stepping. Journal of Neuroscience 29:5681-9

9.  Maier IC, Ichiyama RM, Courtine G, Schnell L, Lavrov I, Edgerton VR, Schwab ME. (2009) Therapeutic effects of anti-Nogo-A treatment and locomotor training: Unraveling combinatorial strategies in spinal cord injury. Brain 132:1426-40

Абстракты (за 5 лет):

1.  Lavrov I, Gad P, Shah P, Zhong V, Roy RR, and Edgerton VR. Modulation of EMG components during stepping with epidural stimulation in different sensory and pharmacological conditions. Society for Neuroscience, 2011 Washington, DC, Planner: 802.08.

2.  Gad P, Woodbridge J, Lavrov I, Zhong V, Roy RR, Sarrafzadeh M, and Edgerton VR. Electronic bridge: Using hindlimb EMG signals to modulate the parameters of forelimb EMG triggered epidural stimulation to improve stepping in spinal rats. Society for Neuroscience, 2011 Washington, DC, Planner: 802.02.

3.  Parag Gad, Jonathan Woodbridge, Igor Lavrov, Yuri Gerasimenko, Hui Zhong, Roland R. Roy, Majid Sarrafzadeh, V Reggie Edgerton. Using Forelimb EMG to control and electronic spinal bridge to facilitate hindlimb stepping after complete spinal cord lesion. BioMed .

4.  Gad P, Woodbridge J, Lavrov I, Gerasimenko Y, Zhong H, Roy RR, Sarrafzadeh M, and Edgerton VR. Development of An Electronic Spinal Bridge Between the Forelimbs and Hindlimbs to Facilitate Quadrupedal Stepping after a Complete Spinal Cord Transection. Society for Neuroscience, 2010 San Diego, CA, Planner: 588.11

5.  Shah P, Lavrov I, Zhong V, Tillakaratne N, Roy RR, and Edgerton VR. Can neuronal circuitries between the forelimbs and hindlimbs mediate functional recovery after spinal cord hemisection in adult rats? Society for Neuroscience, 2010 San Diego, CA, Planner: 684.3

6.  Lavrov I, Nandra M, Choe J, Gad P, Zhong H, Roy RR, Burdick JW, Tai Y. C, and Edgerton VR. Further Development of a High-Density Multi-Electrode Array to Facilitate Stepping and Assess Spinal Cord Function After a Spinal Cord Injury. Society for Neuroscience, 2009 Chicago, IL, Planner: 770.17

7.  Shah P, Gerasimenko Y, Tillakaratne N, Lavrov I, Zhong H, Roy RR, Edgerton VR. Sensory control for selecting specific spinal locomotor circuits in adult chronic spinal rats. Society for Neuroscience, 2009 Chicago, IL, Planner: 176.20.

8.  Zhong H, Hidemi F, Tillakaratne N. J. K., Lavrov I, Edgerton V. R. and Roy R. R. c-fos expression in spinal neurons in response to different hindlimb loading during treadmill locomotion in adult rats. Society for Neuroscience, 2009 Chicago, IL, Planner: 177.10

9.  Gerasimenko YP, Shah P, Tillakaratne NJK, Lavrov I, Zhong H, Roy RR, Edgerton RV. Mechanisms underlying the regulation of different modes of locomotor behavior in adult chronic spinal rats. 36th Congress of the International Union of Physiological Sciences (IUPS), 2009 Kyoto, Japan Planner: P4PM-2-5.

10.  Lavrov I, Nandra M, Choe J, Gad P, Dy C. J, Fong A. J, Tai Y. C, Burdick J. W, Zhong H, Roy R. R, and Edgerton V. R. Spinal cord stimulation with high-density flexible multi-electrode array improves stepping facilitation after a complete spinal cord injury. Dynamics of Neural Microcircuits Symposium, UCLA, 2009 Los Angeles, CA.

ЛЕКЦИИ (Приглашенный лектор)

1.  Task-specific spinal networks, their modulation during motor tasks and reorganization after spinal cord injury. (October, 2011), UTB, Brownsville, TX.

2.  Spinal cord reorganization after a complete spinal cord injury: mechanisms of stepping facilitation and role of sensory input. (September, 2008), Cleveland Clinic, Cleveland, OH.

3.  Neuronal reorganization after spinal cord injury, strategy for neurorehabilitation. (April, 2008), LA Biomed, Los Angeles, CA.

4.  Spinal cord electrical stimulation: experimental and clinical studies. (May, 2002), “Electrical Stimulation Congress 2002”, Moscow, Russia.

ПАТЕНТЫ

1. WOA3 High density epidural stimulation for facilitation of

locomotion, posture, voluntary movement, and recovery of autonomic, sexual,

vasomotor, and cognitive function after neurological injury. Inventors: Angeli

CA, Burdick J, Edgerton VR, Gerasimenko Yu, Harkema SJ, Hodes J, Lavrov I,

Nandra MS, Roy RR, Tai YC.

2. WO A parylene-based microelectrode array implant for spinal cord

stimulation. Inventors: Tai YC, Nandra MS, Edgerton VR, Roy RR, Gerasimenko

Yu, Burdick J, Harkema SJ, Angeli CA, Rodger DC, Fong A, Lavrov I.

ГРАНТЫ

1. Spinal epidural electrode array to facilitate standing and stepping after SCI. NIH

Bioengineering Research Partnerships (BRP), Co-Investigator (), NIH

1R01 EB Edgerton (PI)

2. Identity of sensory and spinal neurons that generate loadbearing stepping.

Paralyzed Veterans of America (PVA), Co-Investigator () Award ID:

2527, Roy, Roland (PI)

3. Interactions of Serotonergic Facilitation and Robotics in Spinal Learning. Co-

Investigator () NIH 1 R01HD, Edgerton (PI).

4. Central Pattern Generators activation in decerabrated and spinal cats. Personal

grant for the young investigators. Principal Investigator (2002) Russian

Foundation for Basic Research (RFFI) 296.

5. Interneuronal mechanisms for the control of walking. Co-Investigator (2001-

2005) The Kentucky Spinal Cord and Head Injury Research Trust, Cheng (PI)

6. Mechanisms of spinal cord locomotor activity regeneration in absence of

supraspinal influences. Co-Investigator (2002) Russian Foundation for Basic

Research (RFFI) , Gerasimenko (PI).

7. Mechanisms of Central Pattern Generator activation in decerabrated and

spinalized animals under nonspecific stimulation of the spinal cord. Co-

Investigator (2002) Russian Foundation for Basic Research (RFFI) ,

Avelev (PI).

8. Personal travel grant (2000) Russian Foundation for Basic Research.

Куратор Open Lab 'Двигательная Нейрореабилитация'