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Key words: аcute intestinal infections, ecology, agent of infection.

References:

1. , , Химический состав питьевых вод Республики Каракалпакстан // Вестник ККО АН РУз. - Нукус, 1998. - №7. – С.4-12.

2. , , Влияние водного фактора на состояние здоровья населения в Южном Приаралье // Журнал теоретической и клинической медицины. – Ташкент, 2006. - №5. - С.40.

3. Методические рекомендации по ротавирусной инфекции: этиология, эпидемиология, клиника, лечение, диагностика и профилактика / [и др.] // Утв. приказом по МЗ РУз № 000 от 21.09.07 г. – 5 c.

4. , Микробиоценоз толстого кишечника у детей Южного Приаралья // Эпидемиология и инфекционные болезни.- М.: Медицина, 2000. - №6. - С.42-43.

5. , , Смертность от инфекционных болезней в различных регионах мира // Эпидемиология и инфекционные болезни. – М.: Медицина, 2006. - № 3. - С.59.

6. Rustamov E. A., Poslavsky A. N., Chernov V. Yu., Dorokhov L. A. Water and swamp bird population as a component of biodiversity of the ecosystems in the Amu-Darya and adjacent lakes. In Ekological reswarch and monitoring of the Aral Sea deltas. A basis for restoration. // UNESCO Aral sea Project 1992-1996 final Scientific reports, 1999.

Information about the author:

Madreimov Amet – candidate of medical sciences, head of the Department of Gigiene of Nukus branch of Tashkent Pediatric Medical Institute, mobile phone 8-361-577-53-52, е-mail: *****@***ru

1140

© M. D. Akhmedova, N. A. Zakhidova, 2009

UDC 616.34-008.39-053.2/.6-07

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Akhmedova M. D., Zakhidova N. A. Endogenous intoxication syndrome in children with mixed intestinal parasitic diseases // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2009. - № 3 (32). – P. 189-192.

State Educational Establishment «Tashkent Medical Academy» of the Ministry of Health of the republic of Uzbekistan, 100109, Tashkent, Farobi str., 2, tel.: 998-(71)-150-78-25,fax: 998-(71)-218-59-48, е-mail: *****@***uz; *****@***ru; *****@***ru

Summary: Parameters of endogenic intoxication and POL in children with intestinal parasitic diseases were studied. Obtained results show that interactions of medium-sized peptides with parameters of POL and AOS are of great importance in pathogenesis of parasitic diseases.

Key words: endotoxemia, lipid peroxidation, antioxidant protection, intestinal parasitic diseases

References:

1. Абдиев Т.А. [и др.]. Гельминтозы в Узбекистане / , , // Актуальные проблемы гигиены, токсикологии, эпидемиологии и инфекционных заболеваний в Республике Узбекистан. – Ташкент, 2005. - С.148.

2.  Ситуация по гельминто-протозойным болезням в Узбекистане / , , // Вестник врача. - 2007. - №1. - С.75-76.

3.  Лямблиоз у детей // Независимое издание для практикующих врачей. – 2004. - №5.

4.  Воспаление как общебиологическая реакция / , , . - Л., 1989. - С.143-160.

5.  Эндотоксикоз в хирургической клинике / , . – СПб, 1995.

6.  Молекулы средней массы как интегральный показатель метаболических нарушений / , // Клин. лаб. диагностика. - 2007. -№6. - С.3-8.

7.  Гельминтозы органов пищеварения / В. Лучшев, А. Бронштейн, Н. Малышев // Медицинская газета. – 2007. - №1. – С.8-10.

8.  Клиническая оценка результатов лабораторных исследований / , . - М., 2002.

Information about the authors:

Akhmedova Muborak Djalilovna – doctor of medicine, professor, head of the Resarch Institute of Epidemiology, Microbiology & Infection Diseases, head of infection diseases department, Reshetov str, 2, Tashkent, 100133, Republic of Uzbekistan, tel. (998-71) 1433605, fax (998-71) 2756692, *****@***ru

Zakhidova Nodira Akhmadovna – the post-graduate student of the Tashkent Medical Academy.

1119

© I. N. Borodina, E. V. Kvashnina, 2009

UDC 614.2:612.017.1(470.12)

Borodina I. N., Kvashnina E. V. Efficacy of the national design introduction in the section of additional immunization on an example of Cherepovets // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2009. - № 3 (32). – P. 192-195.

The territorial department of the Federal Service for Supervision in the field of protection of rights of consumers and well-being of a person in the Vologda region in the Cherepovets town, Cherepovets, Sheksninsky, Kaduysky, Ustyuzhensky, Chagodoshchensky, Babaevsky districts, Russia, 162610 Cherepovets, Vologda Region, Lomonosov str., 42, tel.:/fax: (8-820-2) 57-96-44, e-mail: *****@***ru

Summary: Realization of the National design on additional immunization of the population in 2006-2008 has allowed to achieve the decrease of morbidity with the controlled infections up to sporadic level.

Keywords: additional immunization, hepatitis B, rubella, flu, measles.

Information about the authors:

Borodina Irina Nikolaevna - deputy chief of the territorial department of the Federal Service for Supervision in the field of protection of rights of consumers and well-being of a person in the Vologda region in the Cherepovets town, Cherepovets, Sheksninsky, Kaduysky, Ustyuzhensky, Chagodoshchensky, Babaevsky districts. Tel..: (8-820-2 57-71-04.

Kvashnina Elena Vyacheslavovna - leading specialist-expert of the territorial department of the Federal Service for Supervision in the field of protection of rights of consumers and well-being of a person in Vologda region in Cherepovets, Cherepovets, Sheksninsky, Kaduysky, Ustyuzhensky, Chagodoshchensky, Babaevsky districts. Tel.: (8-820-2 57-71-04.

1134

© E. I. Kondratieva, M. G. Romantsov, 2009

UDC 616.988-053.2/.6:615.281

Kondratieva E. I.1, Romantsov M. G.2 Urgent nonspecific ARVI and flu prevention with "Cycloferon" in children in the epidemic season // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2009. - № 3 (32). – P. 195-199.

1State Educational Establishment of Higher Professional Training «Siberian State Medical University», Russia, 634050, Tomsk, Moskovsky prospect, 2, tel.: 8-382-2-53-33-03, fax: 8-382-2-53-33-03.

2State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», Russia, 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel.: (812)543-96-09, fax: (812)140-15-24, e-mail: *****@***com

Summary. The article represents the data on Cycloferon administration to children of 4 to 18 years of age for urgent nonspecific prophylaxis of ARVI and influenza. Children of the principal group received Cycloferon for one month according to the unique regimen. Children of the control group received reference drug Revit according to the same regimen. Influence of Cycloferon onto ARVI and influenza frequency as well as clinical manifestation on the disease and local immunity was assessed. The results obtained show that Cycloferon reduces the frequency and duration of ARVI and influenza in children, lowers the manifestation of intoxication symptoms and catarrhal effects in upper respiratory tract. The positive effect of Cycloferon on local immunity in upper respiratory tract was registered in all the children. The latter was observed right after the therapy and in catamnesis one month latter. Drug tolerance in preschool children and children of primary school age was evaluated as good, and in children of secondary school age as good and satisfactory.

Key words: prophylaxis, influenza and ARVI, local immunity, catamnesis

References:

1.  Лабораторное дело. - 1968. - №1. - С. 28-30.

2.  Система интерферона в норме и при патологии. - М.: Медицина, 1996. - 240 с.

3. Клиническая оценка лабораторных тестов / Под ред. . - М.: Медицина, 1986. - 480 с

4.  Местная защита респираторного тракта у детей. – Томск, 1993. – 276 с.

5.  Эпидемиологические аспекты неспецифической профилактики инфекционных заболеваний. - Вестник РАМН. - 2001. - №11. - С. 25-29.

6. , Применение циклоферона в практике врача-педиатра / Методические рекомендации для врачей-педиатров и студентов медицинских ВУЗов. - СПб., 2000. - 100 с.

7. , , и др. Анаферон детский отечественный иммунокорректор с противовирусной активностью / Пособие для врачей-педиатров, инфекционистов. - М., 2003. - 32 с.

Information about the authors:

Kondratieva E. I. - Doctor of Medicine, Professor, head of the department of Pediatrics of the faculty for Advanced Medical Training of Siberian State University, tel.: 8-3822-53-10-12, *****@***ru

Romantsov Mikhail Grigorievich – Doctor of Medicine, Professor of the department of Infectious Diseases of SEEHPT «Saint-Petersburg State Medical Academy named after I. I.Mechnikov of Roszdrav». chief consultant for scientific and clinical work STPhF “POLYSAN”, 191119 Saint-Petersburg, Ligovsky prospect, tel.: 8-921-967-69-48, 8-812-710-82-25. E-mail: *****@***ru *****@***ru

1182

© E. A. Orishak, A. G. Boitsov, L. Ju. Nilova, 2009

UDC 579. 852. 11: 616. 34 – 008. 87

Orishak E. A., Boitsov A. G., Nilova L. Yu. Study of antagonistic activity of spor-containing probiotics // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2009. - № 3 (32). – P. 199-202.

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