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Research Institute of Epidemiology, Microbiology & Infection Diseases, 2, Reshetov str., Tashkent city, 100133, Republic of Uzbekistan, tel. 8(998-71)-143-36-05, fax 8(998-71)-275-66-92; е-mail: *****@***ru.

Summary:Features of selenium and zinc dynamic in 56 male 18-22 years old patients with convalescence and 16 patients with S. typhi carriery have been correlated with values of phagocyte component of immune system in NBT-test while forming of various outcome of abdominal fever. 24 healthy persons as control groups have been used. In acute phase of clinical manifestation of abdominal fever the high degree of functional-metabolic activity of neutrophils in NBT-test associates with marked reduction of selenium and zinc in blood. In abdominal fever with further S. typhi carriery low activity of neutrophils in NBT-test associates with minor alteration of selenium, and zinc while acute phase of disease, steady and considerable decrease of its’ content in blood while forming of acute convalesce S. typhi carriery.

Key words: abdominal fever, selenium, zinc, NBT-test

References:

1. Валиев микроэлементов на процессы перекисного окисления липидов / , , // Архив патологии. – 1996.- №6. – С. 99.

2. , Шимкевич научной конференции аспирантов и ординаторов 1-го Московского мед. инст. – Москва, 1964. - С. 18-20.

3. Жаворонков состояния у человека / // Архив патологии. – 1983.- №9. – С.77-80.

4. Мусабаев , содержащие селен, в лечении острых и хронических вирусных гепатитов В / , // Инфекция, иммунитет и фармакология. - 1999. - №1. – С. 56-59.

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5. Насоладин между некоторыми микроэлементами в процессе обмена веществ в организме. Обзор / , // Вопросы питания. – 1986. - №6. - С. 9-13

6. Ойвин обработка результатов экспериментальных исследований / // Журнал пат. физиолог. и эксперимент. тер. – 1960. - №4. – C. 76-85.

7. Пелекис метод определения микроэлементов в биологических материалах. Витамины. Вып. VIII. Биохимия витамина Е и селена / , Л. Л Пелекис., . - ”Наукова думка”. - Киев. - 1975. - С. 40-54.

8. ВТ-тест у детей в норме и при гнойно-бактериальных инфекциях / ., // Лаб. дело. - 1978. - №9. – С. 515-518.

Information about the authors:

Gulyamov Nariman Gulyamovich - doctor of medicine, work tel.:8(391) 243-27-21, home tel.: 8(391) 267-89-57.

1147

© M. I.Kuzmin-Krutetcky, D. B. Degterev, D. V. Mazurenko, 2009

UDC 616.342-006:616-073.759

Kuzmin-Krutetsky M. I., Degterev D. B., Mazurenko D. V. Endoscopy in diagnostics and treatment of adenomas of the large duodenal papilla // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2009. - № 3 (32). – P. 88-91.

State Educational Establishment for Additional Professional Training «Saint-Petersburg Medical Academy for Post-Diploma Training of the Federal Agency for Public Health and Social Development of the Russian Federation», 191015, Kirochnaya str., 41, tel.: 272-52-06, fax: 273-00-39, e-mail: *****@***spb. ru

Summary: Endoscopic method’s of diagnostic and treatment of adenoma of Vater have unquestionable advantage beside other method’s diagnostic and treatment.

Keywords: adenoma of the large duodenal papilla, endoscopy, endoscopic retrograde pancreatocholangography, endoscopic papillosphincterotomy.

References:

1. Эндоскопическая диагностика и лечение доброкачественных новообразований большогодуоденального сосочка (БДС) / , , Балалыкин, Д. А., ,, 3 ЦВКГ им. / 3-я международная конференция «Актуальные вопросы эндоскопической хирургии»

2. Aparajita R., et al. Papillary Adenoma of the Distal Common bile Duct Associated with a Synchronous Carcinoma of the Peri - Ampullary Duodenum. JOP. J. Pancreas, 2008.-V.9(2).-P. 212-215.

3. Stolte M. Pscherer C. Adenoma-carcinoma sequence in the papilla of Vater. Scand. Gastroenterology, 1996.-V.31.-P.376-382

4. Elkharwily A., Gottlieb K. The Pancreas in Familial Adenomatosis Polyposis. JOP. J Pancreas, 2008.-V.9(1).-P.9-18

5. Soweid A.,et al. Endosonographic Evaluation of Intraductal Papillary Mucinous Tumors of the Pancreas JOP. J. Pancreas, 2006.-V.5(4).-P.258-265.

6. Oku T., et al. Intraductal Oncocystic Papillary Neoplasm Having Clinical Characteristics of Mucinous Cystic Neoplasm and a Benign Histology. JOP. J.Pancreas, 2007.-V.8(2).-P.206-213.

7. Sato T, Konishi K, Kimura H, Maeda K, Yabushita K, Tsuji M, Miwa A. Adenoma and tiny carcinoma in adenoma of the papilla papilla of Vater--p53 and PCNA. Hepatogastroenterology.1999V.-46.-P.1959-62. (PMID 10430377)

8. Pandolfi M., et al. Endoscopic Treatment of Ampullary Adenomas. JOP. J. Pancreas, 2008.-V. 9(1).-P.1-8.

9. Badalov N., Tenner S., Baillie J. The Prevention, Recognition and Treatment of Post-ERCP Pancreatitis. JOP. J. Pancreas, 2009.-V.10(2).-P.88-97.

Information about the authors:

Kuzmin-Krutetskyi Mikhail Igorevich - doctor of medicine, head of the Chair of Endoscopy State Educational Establishment for Additional Professional Training «Saint-Petersburg Medical Academy for Post-Diploma Training of the Federal Agency for Public Health and Social Development of the Russian Federation», 191015, Kirochnaya str., 41, tel.: 272-52-06, work tel.: (812)313-46-52, mobile phone:8-911-215-72-79,fax: 273-00-39, e-mail: *****@***spb. ru

e-mail: *****@***ru

Degterev Denis Borisovich – candidate of medical sciences, assistant-professor of the Chair of Endoscopy State Educational Establishment for Additional Professional Training «Saint-Petersburg Medical Academy for Post-Diploma Training of the Federal Agency for Public Health and Social Development of the Russian Federation», work tel.: (812)313-46-52, mobile phone 8-911-215-72-79.

Mazurenko Dmitry Vitalyevich-postgraduate of the Chair of Endoscopy State Educational Establishment for Additional Professional Training «Saint-Petersburg Medical Academy for Post-Diploma Training of the Federal Agency for Public Health and Social Development of the Russian Federation» work tel.: (812)313-46-52, mobile phone:8-981-743-94-73.

1166

© N. V. Baryshnikova, E. I. Tkachenko, Y. P. Uspenskiy, 2009

UDC 616.33-002.-07:579.83

Baryshnikova N. V., Tkachenko E. I., Uspensky Yu.P. Problems of helicobacteriosis diagnostics optimization // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2009. - № 3 (32). – P. 91-95.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», Russia, 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel.: (812)543-96-09, fax: (812)140-15-24, e-mail: *****@***com

Summary: «Helic-test» is recommended us clear uninvasive метод for screening detection Helicobacter pylori and estimate of eradication efficacy, especially for children. To increase diagnostic sharpness using at least two methods is bination of «Helic-test» with histological method or polimerase chain reaction is optimal.

Key words: Helicobacter pylori, diagnostic, «Helic-test».

References:

1.  Особенности лабораторной диагностики Helicobacter pylori и клинического течения хронического гастрита и язвенной болезни при бациллярно-кокковом дисморфизме бактерии // Дисс… канд. мед. наук: 14.00.46, 14.00.47. – СПб., 2008. – 136 с.

2. , Хеликобактериоз. – М.: ИД Медпрактика, 2003, - 412 с.

3. Неинвазивные методы диагностики инфекции, вызванной Helicobacter pylori / [и др.] // Педиатрия. – 1999. - №1. – С. 37-41.

4. О причинах вариабельности Helicobacter pylori-ассоциированных гастродуоденальных заболеваний у детей / [и др.] // Русский медицинский журнал. – 2003. – Т.11, №13. – С. 782-786.

5. Brooks H., Ahmed D., McConnell M., Barbezat G. Diagnosis of Helicobacter pylori infection by polymerase chain reaction: is it worth it? // Diagn. Microbiol. Infect. Dis. – 2004. – Vol.50. – P. 1-5.

6. Campilobacter pylori detected noninvasively by the 13C-urea breath test / D. Y. Graham [et al.] // Lancet. – 1987, i. – P. 1174-1177.

7. Fallahi G. H., Maleknejad S. Helicobacter pylori culture and antimicrobial resistance in Iran // Indian J. Pediatr. – 2007. – Vol.74, №2. – P. 127-130.

8. Hirschi A. M., Makristathis A. Methods to detect Helicobacter pylori: from culture to molecular biology // Helicobacter. – 2007. – Vol.12, suppl.2. – P.6-11.

Information about the authors:

Baryshnikova Natalia Vladimirovna - candidate of medical sciences, assistant of the Department of Propedeutics of Internal Diseases of Saint-Petersburg State Medical Academy named after I. I. Mechnikov. work tel.: (8-812) 543-04-60, home tel.: (8-812) 225-53-08, mobile phone: (8-812) 301-33-77, e-mail: *****@***ru

Tkachenko Evgenу Ivanivich – doctor of medical sciences, professor, head of the Department of Propedeutics into Internal Diseases of Saint-Petersburg State Medical Academy named after I. I. Mechnikov. work tel.: (8-812) 543-95-38, home phone: (8-812) 553-03-49, mobile phone: (8-960) 287-84-90, e-mail: *****@***ru

Uspenskiy Yury Pavlovich - doctor of medical sciences, professor of the Department of Propedeutics into Internal Diseases of Saint-Petersburg State Medical Academy named after I. I. Mechnikov. work tel.:: (8-812) 543-95-38, mobile phone: (8-921) 315-27-61, e-mail: *****@***ru

1149

© V. V. Shchedrenok, K. I. Sebelev, A. V. Ivanenko, O. V. Moguchaya, S. V. Zevakhin, M. V. Chizhova, 2009

UDC 616.721.6-018.3-06-08

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