2) Immune complex injury

3) Immunologic tolerance

4) Genetic deficiency of the monocyte/macrophage system

5) Genetic deficiency of the complement system

76. The classic an example of delayed type hypersensitivity is which of the following

1) Arthus reaction

2) Local anaphylaxis

3) Complement-dependent reaction

4) Tuberculin reaction

5) Systemic anaphylaxis

77. Cells which compose the granuloma in type IV hypersensitivity reactions are all of the following, EXCEPT

1) Lymphocytes

2) Erythrocytes

3) Macrophages

4) Epithelioid cells

5) Giant cells

78. Autoimmune diseases involving a single organ or cell type are all of the following, EXCEPT

1) Hashimoto's thyroiditis

2) Goodpasture's syndrome

3) Insulin-dependent diabetes mellitus

4) Myocardial infarction

5) Myasthenia gravis

79. The organs most commonly and seriously damaged in systemic lupus erythematosus are all of the following, EXCEPT

1) Skin

2) Eyes

3) Joints

4) Serosal surfaces

5) Heart and vessels

80. The main morphologic features of Graves' disease include all of the following, EXCEPT

1) Tall and crowded follicular epithelial cells

2) Small papillae into the follicular lumen

3) Lack of fibrovascular cores in papillae

4) Pale colloid with scalloped margins

5) Large leukocytic aggregates in the stroma

81. During the inflammatory response the proper order of white cell events is which of the following

1) Endothelial adherence, margination, phagocytosis, chemotaxis

2) Margination, leukodiapedesis, chemotaxis, phagocytosis

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3) Margination, migration, chemotaxis, stasis

4) Stasis, leukodiapedesis, margination, phagocytosis

5) Leukodiapedesis, stasis, degranulation

82. Fluid that collects during acute inflammation and that has a protein content exceeding 3 g/dl and a specific gravity exceeding 1.015 is referred to as

1) Edema

2) Effusion

3) Transudate

4) Serum

5) Exudate

83. The adherence of neutrophils and monocytes to the vascular endothelium prior to movement into the extravascular space is called

1) Margination

2) Diapedesis

3) Pavementing

4) Emigration

5) Clotting

84. Mediators of increased vascular permeability in acute inflammatory responses include all of the following substances, EXCEPT

1) Leukotriene E4

2) Complement complex C5b-9

3) Leukotriene C4

4) Bradykinin

5) Platelet-activating factor

85. Activation of Hageman factor leads to activation of all of the following catalytic systems, EXCEPT

1) Complement system

2) P-450 (mixed-function oxidize system)

3) Kinin system

4) Fibrinolytic system

5) Coagulation system

86. The inflammatory response leads to all of the following consequences, EXCEPT

1) Isolation of infected tissues

2) Inactivation of causative agents

3) Neutralization of toxins

4) Removal of devitalized tissue debris

5) Obesity

87. Acute inflammation includes all of the following types, EXCEPT

1) Purulent

2) Fibrinous

3) Granulomatous

4) Serous

5) Catarrhal

88. “Hairy heart” is an example of which of the following types of inflammation

1) Purulent

2) Fibrinous

3) Serous

4) Catarrhal

5) Hemorrhagic

89. Purulent inflammation is characterized by which of the following features

1) Neutrophil infiltration with tissue lysis

2) Fibrin deposition

3) Mucus production

4) Lymphocyte infiltration

5) Neutrophil infiltration

90. Which of the following types of inflammation is found in lobar pneumonia

1) Purulent

2) Fibrinous

3) Serous

4) Catarrhal

5) Granulomatous

91. The most reliable histopathologic evidence of chronicity in an inflammatory process in the organs is which of the following

1) Hemorrhages

2) Leucocytic infiltrates

3) Blood vessels destruction

4) Interstitial fibrosis

5) Councilman's bodies

92. A large aggregate of epithelioid cells is seen in a microscopic section of an ovary removed at surgery. Your diagnosis is

1) Granulation tissue

2) Pyogenic granuloma

3) Granulosa cell tumor

4) Granulocytosis

5) Granuloma

93. The granuloma in sarcoidosis is composed predominantly of which of the following cells

1) Monocytes/macrophages

2) Neutrophils

3) Eosinophiles

4) Plasma cells

5) Lymphocytes/fibroblasts

94. The granuloma in military tuberculosis is composed predominantly of which of the following cells

1) Fibroblasts

2) Epithelioid cells

3) Epithelial cells

4) Plasma cells

5) Neutrophils

95. The granulomatous infiltrate in tertiary syphilis is composed predominantly of which of the following cells

1) Neutrophils

2) Monocytes/macrophages

3) Plasma cells

4) Eosinophiles

5) Lymphocytes

96. What type of necrosis can be found in skin sarcoidosis

1) Coagulative

2) Liquefaction

3) Enzymatic fat

4) Caseous

5) Fibrinoid

97. Miliary lung tuberculosis is characterized by which of the following types of the inflammation

1) Granulomatous

2) Serous

3) Fibrinous

4) Suppurative

5) Hemorrhagic

98. Most comprehensively the chronic inflammation is characterized by all of the following features, EXCEPT

1) Infiltration with macrophages

2) Tissue destruction

3) Healing by connective tissue

4) Self-limited duration

5) Infiltration with lymphocytes and plasma cells

99. What type of necrosis can be found in tuberculous granuloma

1) Coagulative

2) Liquefactive

3) Caseous

4) Enzymatic fat

5) Fibrinoid

100. Typical tyberculous granuloma to characterized by all of the following features, EXCEPT

1) Plasma cells

2) Central necrosis

3) Epithelioid cells

4) Langhans' giant cells

5) Lymphocytes

101. A malignant tumor is characterized by all of the following features, EXCEPT

1) Increased abnormal tissue mass

2) Uncoordinated invasive growth

3) Relatively autonomous growth

4) Decreased abnormal tissue mass

5) Metastases

102. The growth of neoplasm is critically resulted from which of the following factors

1) Localization

2) Tumor stroma

3) Neutrophil immigration

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