Сборник тестовых заданий по патологической анатомии (стр. 8 )

2) Alcohol abuse

3) Obesity

4) Hepatitis В

5) Diabetes mellitus

184. Injury to the liver associated with an influx of acute or chronic inflammatory cells is termed as

1) Liver regeneration

2) Liver cirrhosis

3) Hepatoma

4) Liver degeneration

5) Hepatitis

185. The symptom of yellow discoloration of the skin and sclera, organs and mucosae is referred to as

1) Melanosis

2) Vitiligo

3) Nevi

4) Cyanosis

5) Jaundice

186. Unconjugated bilirubin is characterized by all of the following, EXCEPT

1) Insoluble in water

2) Tightly complexed to serum albumin

3) Not excreted in the urine

4) Diffuses into tissue and produce toxic injury

5) Increased only in impaired bile flow

187. Conjugated bilirubin is characterized by all of the following, EXCEPT

1) Water-soluble

2) Nontoxic

3) Loosely bound to albiimin

4) Excreted in the urine

5) Induces kernicterus

188. Hepatitis С is characterized by all of the following features, EXCEPT

1) Parenteral route of transmission

2) Possible sexual and vertical transmission

3) High rate of progression to chronic disease

4) Low rate of progression to cirrhosis

5) Absence of effective immunity

189. All of the following syndromes are characterized by hereditary hyperbilirubinemias, EXCEPT

1) Crigler-Najjar type II

2) Gilbert's

3) Crigler-Najjar type III

4) Dubin-Johnson's

5) Rotor's

190. The morphologic alterations that cause liver failure are all of the following, EXCEPT

1) Small fatty droplets in hepatocytes

2) Massive hepatic necrosis

3) Acute inflammation

4) Cirrhosis

5) Chronic inflammation

191. Chronic renal failure produce increased serum levels of all of the following substances, EXCEPT

1) Billirubin

2) Aldosterone

3) Phosphate

4) Parathormone

5) Renin

192. Uremia is associated with all of the following abnormalities, EXCEPT

1) Peripheral neuropathy

2) Gastritis

3) Polycythemia

4) Pericarditis

5) Diffuse alveolar damage

193. Glomerular injury caused by circulating immune complexes occurs with all of the following disorders, EXCEPT

1) Syphilis

2) Goodpasture's syndrome

3) Hepatitis В

4) Systemic lupus erythematosus

5) Lung cancer

194. Diabetes mellitus is associated with all of the following renal disorders, EXCEPT

1) Diffuse glomerulosclerosis

2) Nodular glomerulosclerosis

3) Benign nephrosclerosis

4) Urate nephropathy

5) Acute pyelonephritis

195. All of the following conditions predispose to urolithiasis, EXCEPT

1) Sickle cell nephropathy

2) Hyperparathyroidism

3) Gout

4) Proteus pyelonephritis

5) Enteric hyperoxaluria

196. The factor least likely to cause acute pyelonephritis is which of the following

1) Pregnancy

2) Nephrolithiasis

3) Catheterization of the bladder

4) Prostate hypertrophy

5) Septicemia

197. Mesangial cells can be characterized by all of the following properties, EXCEPT

1) Ingestion of macromolecules

2) Interaction with macula denza cells

3) Ability to contract

4) Production of renin

5) Production of basement membrane proteins

198. All of the following statements correctly describe analgesic abuse nephropathy, EXCEPT

1) It is characterized by the tubulointerstitial component

2) It is often caused by phenacetin

3) It causes an inability of kidneys to concentrate urine

4) It often improves with drug withdrawal

5) It predisposes to the development of renal cell carcinoma

199. Histologic features of malignant nephrosclerosis include all of the following, EXCEPT

1) Fibrinoid necrosis of arterioles

2) Medial thickening of arterioles

3) Fibromascular dysplasia of the renal artery

4) Renal artery thrombosis

5) Kidney infarct

200. Obstetrically related renal diseases includes all of the following, EXCEPT

1) Nephrocalcinosis

2) Diffuse cortical renal necrosis

3) Adult hemolytic uremic syndrome

4) Eclampsia

5) Hydronephrosis

201. Insulin-dependent diabetes mellitus is characterized clinically by all of the following features, EXCEPT

1) Normal or increased blood insulin level

2) Normal weight

3) Anti-islet cell antibodies in the serum

4) Ketoacidosis

5) Decreased blood insulin level

202. Clinically non-insulin-dependent diabetes mellitus is characterized by all of the following features, EXCEPT

1) Obesity

2) Decreased blood insulin level

3) Absence of anti-islet-cell antibodies

4) Absence of ketoacidosis

5) Normal or increased blood insulin level

203. All of the following pathogenetic mechanisms may contribute to the development of type I diabetes, EXCEPT

1) HLA-linked genes and other genetic loci

2) Immune response to normal beta-cells

3) Immune response to altered beta-cells

4) Peripheral tissue insulin resistance

5) Molecular mimicry of beta-cells after viral infection

204. All of the following pathogenic mechanisms may lead to the development of type II diabetes, EXCEPT

1) Primary beta-cell defect