Сборник тестовых заданий по патологической анатомии (стр. 6 )

2) Giant platelets in the peripheral blood

3) Teardrop-shaped red cells in the peripheral blood

4) Elevated leukocyte alkaline phosphatase levels in the serum

5) Massive splenomegaly

133. Transformation to acute leukemia occurs as a complication of all of the following disorders, EXCEPT

1) Paroxysmal nocturnal hemoglobinuria

2) Myeloid metaplasia with myelofibrosis

3) Aplastic anemia

4) Hairy-cell leukemia

5) Polycythemia vera

134. Intermediate grade lymphomas include all of the following variants, EXCEPT

1) Follicular, predominantly large-cell lymphoma

2) Follicular, predominantly small cleaved cell lymphoma

3) Diffuse, small cleaved cell lymphoma

4) Diffuse, mixed small - and large-cell lymphoma

5) Diffuse large-cell lymphoma

135. Chronic myelogenous leukemia is characterized by all of the following features, EXCEPT

1) Lack of alkaline phosphatase in circulating neutrophils

2) Splenomegaly

3) Transition to acute leukemia

4) Philadelphia chromosomes in stem cells

5) Excellent response to chemotherapy

136. The diagnostic cell for Hodgkin's disease is which of the following

1) Lymphocyte

2) Foam cell

3) Reed-Sternberg cell

4) Myeloma cell

5) Macrophage

137. Subtypes of Hodgkin's disease include all of the following, EXCEPT

1) Nodular sclerosis

2) Mixed cellularity

3) Lymphocytepredominance

4) Nodular amyloidosis

5) Lymphocyte depletion

138. The diagnostic cell for multiple myeloma is which of the following

1) T lymphocyte

2) Eosinophile

3) Reed-Sternberg cell

4) Plasma cell

5) В lymphocyte

139. Multiple myeloma is characterized by the abnormal accumulation in tissues of which of the following substances

1) Hyaline

2) Lipofuscin

3) Amyloid

4) Hemosiderin

5) Melanin

140. Burkitt lymphoma is characterized by which of the following histologic appearances

1) "Starry sky" appearance

2) Infiltration of plasma cells

3) Presence of foam cells

4) Presence of Reed-Sternberg cells

5) "Glassy " appearance of the cell

141. Blood vessels affected in atherosclerosis are which of the following

1) Aorta only

2) Aorta and large arteries

3) Large arteries and veins

4) Large veins

5) Aorta and arterioles

142. Blood vessels affected in systemic hypertension are which of the following

1) Arterioli

2) Aorta and large arteries опту

3) Aorta only

4) Large arteries and veins

5) Venules

143. The cells accumulating cholesterol or cholesterol esters in atherosclerotic plaque are which of the following

1) Neutrophils

2) Lymphocytes and macrophages

3) Macrophages and smooth muscle cells

4) Mesenchymal cells

5) Giant cells

144. Material deposited in arteriolar walls in systemic hypertension is which of the following

1) Amyloid

2) Glycogen

3) Cholesterol or cholesterol esters

4) Lipoprotein

5) Hyaline

145. The consequences of atherosclerosis are all of the following, EXCEPT

1) Myocardial infarction

2) Cardiomyopathy

3) Cerebral infarct

4) Gangrene of lower extremities

5) Abdominal aortic aneurysm

146. The complications of atheromatous plaque are all of the following, EXCEPT

1) Thrombus formation

2) Plaque rupture

3) Plaque malformation

4) Calcification

5) Hemorrhage

147. The antihypertensive substances, produced in the kidney are all of the following, EXCEPT

1) Prostaglandines

2) Urinary kallikrein-kinin system

3) Platelet-activating factor

4) Nitric oxide

5) Thromboxane

148. On gross appearance, the kidneys in benign systemic hypertension are characterized by all of the following features, EXCEPT

1) Reduced in size weight

2) Fine granular cortical surface

3) Grain leather-like cortical surface

4) Cortical hemorrhages

5) Narrowed cortical surface on section

149. All of the following attributes be used to designate the atherosclerotic plaque, EXCEPT

1) Fibrinous

2) Fibrous

3) Fibrofatty

4) Atheromatous

5) Fibrolipid

150. The major nonmodifiable risk factors for atherosclerosis are all of the following, EXCEPT

1) Age

2) Increased water resorption

3) Male gender

4) Family history

5) Genetic abnormalities

151. Coronary artery supplying blood to the posterior portion of the interventricular septum is which of the following

1) Left main coronary artery

2) Left anterior descending artery

3) Right coronary artery

4) Left circumflex coronary artery

5) Proximal marginal coronary artery

152. Coronary artery supplying blood to the anterior part of the interventricular septum is which of the following

1) Posterior interventricular coronary artery

2) Left anterior descending artery

3) Right coronary artery

4) Left circumflex coronary artery

5) Proximal marginal coronary artery

153. Changes in the aging heart are all of the following, EXCEPT

1) Decreased left ventricular cavity size

2) Epicardial coronary arteries tortuosity

3) Decreased subepicardial fat

4) Brown atrophy of the myocardium

5) Increased number of inflammatory cells in the myocardium

154. Symptoms of cardiac dysfunction include all of the following, EXCEPT

1) Failure of the pump itself

2) Disorders of blood coagulation

3) Obstruction of blood flow

4) Regurgitant blood flow

5) Disorders of cardiac conduction

155. Microscopically, most cases of acute myocarditis are characterized by all of the following features, EXCEPT

1) Nonspecific inflammatory infiltrate

2) Variable amount of the interstitial edema

3) Variable degree of myofiber degeneration

4) Marked fibrosis of the interstitium

5) Variable degree of myofiber necrosis

156. Nonbacterial thrombotic endocarditis is characterized by all of the following features, EXCEPT

1) Mitral and/or aortic valve involvement

2) Tricuspid valve involvement

3) Small (1 to 5 mm), sterile verrucae

4) Verrucae along the line of valve closure

5) Systemic embolism

157. Acute rheumatic carditis is characterized by all of the following features, EXCEPT

1) Unremarkable gross appearance of the heart

2) Aschoff bodies in myocardium

3) Diffuse nonspecific myocarditis

4) Aschoff bodies in the capsule of joints

5) Tigered effect

158. The correct order of histologic phases in the development of Aschoff bodies is which of the following

1) Exudative - proliferative - fibrous

2) Granulomatous - late - exudative

3) Acute - chronic - healed

4) Nonspecific - specific

5) Early - pathognomonic – intermediate